The Portuguese paper claims Guarin, who was heavily linked with a move to Chelsea and Manchester United earlier this month, has not turned up for training on Wednesday after his proposed deal to Juventus broke down.
The £15m-rated Colombian international was reportedly part of a swap deal involving Juventus striker Mirko Vucinic - but the plug was pulled on the agreement late on.
Chelsea, United, Napoli, Tottenham and Paris Saint-Germain have all been tipped to make a move for the 26-year-old.
And the report claims the fact he has not shown up for training could be taken as Guarin attempting to force Inter Milan into letting him go.
But there is also another potential explanation. Sky Sports Italia have reported that Guarin has actually been granted two days off, and that his absence from training has been agreed with the club.
Regardless, it's clear Guarin is desperate to leave as the Sky Sports Italia report goes on to say that the player's agent will meet club officials to discuss his future with the player all but resolved to leaving.
Chelsea have completed a deal for a midfielder already this month. Jose Mourinho snapped up Nemanja Matic for £21m from Benfica.