Harlequins travel to Paris to face Stade Français in their Amlin Challenge Cup quarter-final at the Stade Jean Bouin.
The Quins will be looking to reach the semi-final stage for the first time since winning the trophy in 2011, where they beat Stade 19-18 in a pulsating final.
And, the visitors will have England international Joe Marler in their side, with the prop set to make his 100th appearance for the club. It comes just days after he signed a new contract at Harlequins.
The Quins make two changes from their win against London Irish in the Aviva Premiership last week, bringing in centre Tim Molenaar and second row Charlie Matthews, in place of Jordan Turner-Hall and George Robson.
This is their first Amlin Cup match of the season, having dropped down as fourth best runner-up in the main European competition, the Heineken Cup.
As for Stade Français, they have reached the semis in the last three seasons, losing out in the final last year to Leinster as well as back in 2011.
In this year’s tournament, they topped Pool 5, narrowly qualifying above London Irish, after having a better head-to-head record on points.
The hosts have made a massive 12 changes to their squad, following their 32-22 defeat to Racing Metro in the Top 14 last time out.
The winner of this will face Northampton Saints in the last four, after they beat Sale Sharks 28-14 in an all-English encounter last night.
Stade Français: Lydon, Kingi, Williams, Danty, Camara, Steyn, Daguin, Zhvania, Sempere (capt), Kubriashvili, Wegner, Garrault, Missoup, Lyons.
Replacements: Van Vuuren, Frou, Slimani, Van Zyl, Rabadan, Mallet, Cocagi, Arias.
Harlequins: Brown, Lindsay-Hague, Molenaar, Turner-Hall, Smith, Evans, Care, Marler, Ward, Sincklet, Matthews, Robson, Wallace, Robshaw (capt), Easter.
Replacements: Buchanan, Lambert, Doran-Jones, Merrick, Guest, Dickson, Botica, Sackey.
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