Clint Dempsey is ready for an "athletic" Colorado Rapids, while Vancouver Whitecaps look to halt a win-less run, and Montreal Impact are hoping for their first victory in this weekend's MLS action.
Seattle Sounders FC star Dempsey faces the Rapids side that his team knocked out of the 2013 MLS Cup play-offs. It will be far from easy though, as the Rave Green were beaten 5-1 in Colorado last year:
"We know they're an athletic team. They beat us pretty decisively at their place, which is something we’re looking to make sure doesn’t happen again," the 31-year-old revealed.
"We need to make sure we’re prepared for them because they do have quality going forward," the former Fulham man continued.
USA captain Dempsey has built an impressive strike partnership with Obafemi Martins in the early part of this season, scoring six and two goals respectively, and the pair will look to continue their fine form this weekend.
And Dempsey was confident in his own team's ability to cause the opposition problems ahead of the challenging tie:
"We don’t change how we play. We link up, we create opportunities and we’ve got a good understanding of where we are on the field."
Meanwhile, Vancouver go into their clash with an unbeaten Real Salt Lake looking to arrest a run of three matches without a win. The Whitecaps gained an impressive point in their second consecutive game against the LA Galaxy, but haven't tasted victory since their 2-1 triumph over the Houston Dynamo on March 29.
And former Scotland international Kenny Miller believes they have shown progress in recent games:
"They’re probably two of the better teams in the league that we’ve faced over the last three games so we can take heart from the performances.
"Obviously the results could have been a little bit better, but we’ve got to take the positives and look forward to another really tough test on Saturday."
Another side that are having a tough time are Montreal, who are yet to pick up a win this season and have accumulated just three points.
Last time out, the Impact were thrashed 4-0 by a ruthless Sporting Kansas City, but Impact's sporting director Nick de Santis remains optimistic:
"I think we’re only a win away from relieving a lot of pressure from everyone."
The 46-year-old said the club understands their fans' frustrations, claiming that this tricky start to the season will improve the team in the long-term:
"It's going to make us better for getting through these difficult moments if we all believe in the direction we're going, and the players and the team stay positive."
Elsewhere, the San Jose Earthquakes and the Portland Timbers join Montreal in their hunt for a first win, while FC Dallas will look to extend their lead at the top of the table as they travel to DC United.
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