Manchester United midfielder Daley Blind is facing up to six weeks on the sidelines after suffering medial ligament damage during Holland's European Championship qualifier against Latvia on Sunday evening.
Blind lasted less than 20 minutes on his 25th appearance for the Dutch national side, collapsing in agony after Latvia forward Eduards Visnakovs landed on his knee.
The £14 million man did manage to hobble off without help from Netherlands medical staff to raise hopes the problem wasn't too serious, but unfortunately manager Guus Hiddink had some bad news on that front after the full-time whistle.
United in the midst of a full-blown injury crisis
After watching his side beat Latvia 6-0 Hiddink was asked about Blind and delivered an early prognosis that could see the 24-year-old ruled out until Christmas.
Hiddink said: "It doesn't look good. It is his medial ligament. It could be a strain but also be a tear, so that is a big blow."
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Three huge injury blows suffered during international break
Blind's knee problem has come at a terrible time for United, less than 24 hours after another key first-team star in David de Gea suffered a dislocated finger playing for Spain.
Even the hugely experienced Louis van Gaal must be reeling from an almost unprecedented run of injury problems at United, which the Daily Mail report has seen a player ruled out at least once every three days since he took charge at the Theatre of Dreams.
United also saw Michael Carrick withdraw from England duty before a ball had been kicked last week through injury, leaving United desperately short of midfield cover to match their defensive woes.
Arsenal test looming large
Van Gaal will definitely be without Blind, Carrick and De Gea for this Saturday's clash with Arsenal at the Emirates, helping build a gloom around United that even Chris Smalling's return from suspension won't solve.
Marcos Rojo, Phil Jones and Jonny Evans are all still sidelined to boot, which essentially means Smalling and Paddy McNair are shoe-in's to start against the Gunners if they can stay healthy this week.
Attack will almost certainly be United's only option in North London, as two huge sides with problems aplenty gear up for what has the makings of a must-win clash this weekend.