Manchester United are expected to make an announcement on Tuesday confirming the extent of Robin van Persie's ankle injury.
The Netherlands international limped off during United's 1-0 defeat to Southampton on Sunday - and the Red Devils are poised to make a statement within the coming hours, according to Sunday World journalist Kevin Palmer.
Van Persie was forced to miss Monday's Ballon d'Or ceremony in Zurich - he was nominated for the coveted Puskas Award for his stunning diving header for the Netherlands against Spain at the World Cup finals - because of his injury, indicating that it could be more serious than first feared.
Van Persie missed Ballon d'Or ceremony
The Dutch striker tweeted: "On advice of the club medical staff I am unable to fly out to Zurich tomorrow to attend the FIFA Ballon d'Or gala."
Van Persie is a serious doubt for Manchester United's Premier League clash against Queens Park Rangers on Saturday. Louis van Gaal's side are without a win in three matches and could lose their position inside the top four to Arsenal if they fail to secure maximum points at Loftus Road.
If Van Persie is ruled out of this weekend's match, Van Gaal is likely to bring Radamel Falcao back into the fold.
The Colombia international was left out of United's 18-man squad for the defeat to Southampton at the weekend - a decision which received some strong criticism from supporters - and is reportedly considering his options following Van Gaal's surprise snub.
Falcao is concerned that Van Gaal is treating him harsher than other members of the squad - such as Van Persie, who has retained his place in Manchester United's starting line-up despite a string of poor performances at times this season.
Van Persie's decline
Van Persie has scored eight goals in 17 appearances this term, but there are fears that Manchester United may have already seen the best of the 31-year-old.
The £24 million signing from Arsenal played an instrumental role in helping United win their 20th league title in 2013 - but admitted the departure of Sir Alex Ferguson affected him.
Van Persie struggled to find his form under the management of David Moyes and finished the 2013-14 campaign with 12 Premier League goals from 21 appearances.
It remains to be seen how this latest injury setback affects his Manchester United career - although it's clear that Van Gaal has the utmost confidence in the striker he made captain of the Netherlands national team.