Manchester United have just gone top of the Premier League table after a confident performance against Sunderland at the weekend.
The Red Devils go into Champions League matchday two after three wins on the bounce - however, that win streak dates back to their last CL game, where they lost 2-1 against PSV Eindhoven.
United's possession-based style proved for expert ball retention for the vast majority of the match, but PSV were able to score twice on the break and hold on for a home win.
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Van Gaal's men go into a tie with VFL Wolfsburg, who beat CSKA Moscow 1-0 in their first match, with young starlet Julian Draxler grabbing the lone goal.
The Wolves have had a quietly solid start to their Bundesliga campaign, and though they lie fourth in the table they have only lost one of their seven matches.
Their star from last season Kevin de Bruyne has moved back to England after dominating the league in 2014-15, but young the German Draxler has stepped in and filled De Bruyne's role.
Their counter attack style proved a winning tactic against CSKA on match day one, but this is their first European campaign since before 2010 so they are potentially vulnerable in big games.
Brazilian defender Naldo is their star man at the back, and it will be his job to stop the speedy attacking players like Memphis Depay and Anthony Martial.
United, unlike Die Wolfe, are accustomed to playing in Europe and could be capable of a deep run in the competition.
While Louis van Gaal will be expecting to reach the knockout stages and possibly go further, the men from Manchester will find themselves in the Europa League if they are not careful.
It is not easy to come back into first place in the Champions League group stages after losing your first two games, so this game is truly a must-win.
United are at home for the Wolfsburg fixture, and they have a great record at Old Trafford this season. However, they have been guilty of playing far too slow and allowing bad teams to defend sufficiently by not breaking their defenses down.
Wolfsburg may not be the caliber of a Manchester City or an on-form Chelsea, but they are capable of breaking with pace.
In their match against Sunderland, the Red Devils looked dangerous when they played that classic Manchester United direct football.
Memphis Depay touched in a pass from Juan Mata that stemmed from a 40-yard ball played by Daley Blind, making for a two-pass attacking move.
However, there were also moments where their players were not running with the ball into space and simply allowing the Black Cats to set themselves up.
Sunderland may not be very good defensively, but when a center back pairing better than the one they possess faces United - like Naldo and Dante - it could be a different story altogether.
My prediction for Manchester United vs. Wolfsburg on September 30: Manchester United 2-0 Wolfsburg - let us know yours!