It was a tough Sunday all round for the Rex Ryan and the Buffalo Bills.
Not only did the head coach see his team lose 24-10 to the New York Giants, but the Bills were handed some worrying injury news that could have a far longer lasting effect that the week four defeat.
As reported by Fox Sports' Mike Garafolo, an MRI scan has revealed a "new tear" in the hamstring of running back LeSean McCoy - a setback that could lead to a further four weeks on the sidelines.
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McCoy had, until missing out on today's game against the Giants, been playing hurt through the first few weeks of the season. But, rather than getting better, it appears that McCoy's hamstring issue has only gotten worse.
With the Pro Bowl running back having insisted on Friday that he wouldn't return to the gridiron until he felt 100-percent healthy, this latest report will likely have Buffalo fans concerned that they could be without McCoy for a considerable chunk of the campaign.
Although missing McCoy will be a blow for the AFC East franchise as they look to build on a 2-2 record, the veteran's stand in has put in some solid performances himself.
Karlos Williams has 273 yards all told through four games, adding four touchdowns in the process.
However, with the Bills having handed out mega bucks over the offseason when adding McCoy via a trade with the Philadelphia Eagles, being without the star until mid-season is certainly not what they would have hoped for.
Bills fans: Was it a mistake to trade for LeSean McCoy? Have your say in the comments below...