Luis Suarez has played in the Premier League, the World Cup and the Copa America, facing formidable foes in the process.
The controversial Uruguayan has found himself so frustrated with the likes of Branislav Ivanovic and Georgio Chiellini that he has even resulted to taking chunks our of their arms to try and get past.
Suarez may have sat plenty of defenders down during his time with Premier League outfit Liverpool, but he also came up against several brick walls.
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Despite the titanic tussles with the likes of John Terry and Vincent Kompany, Suarez did not meet his toughest opponent until he played in his first Clasico fixture for Barcelona. The 28-year-old revealed that no defender has given him a harder time than Real Madrid's Sergio Ramos.
Speaking of Sergio Ramos, he told Mundo Deportivo: “He’s the toughest defender that I’ve come up against. He’s very strong, competitive and has plenty of experience. That’s one of the reasons why there is added importance on the goal I scored against Real Madrid at Camp Nou.”
Ramos will have another chance to keep Suarez quiet when Barcelona travel to the Bernabeu on November 21. Currently only separated by goal difference at the top of the table, the game, as always, promises to be a significant decider in the La Liga title race.
And Ramos, who was strongly linked with a move to Manchester United in the summer, faces a tough task himself. Suarez has scored ten goals across all competitions already this season, helping to make up for the absence of the injured Lionel Messi.
And, if reports are to be believed, the diminutive Argentinian is on track to return in time for the crunch clash. Good luck, Sergio.