Adam Voges and Shaun Marsh broke records and piled on the misery for the West Indies as Australia took total command of the first Test in Hobart.
The highest fourth-wicket stand in Test history - 449 - took the home team to 583 for four before they declared at lunch with Voges unbeaten on 269 and Marsh having made 182.
Off-spinner Nathan Lyon then claimed three for 43 as the tourists struggled with the bat and despite an unbeaten 94 from Darren Bravo could only reach 207 for six at stumps, still 376 behind.
Marsh and Voges came together late on the first morning and their stand was already worth 215 when play resumed on Thursday - and when 11 runs, including four overthrows, came from the day's third over it was clear the Windies' situation was not going to improve.
Marsh survived a huge lbw appeal by Jason Holder and reached 150 with a single off Jerome Taylor shortly afterwards - an over after Voges reached his double century when he pushed his 226th ball, from Holder, for a single.
Voges took the team's total past 500 with the first of three successive boundaries off Kemar Roach and the partnership to 400 with a single off the same bowler, before spinner Jomel Warrican conceded 19 runs in an over with three fours from Voges and a six by Marsh.
That over made it the highest partnership ever against the West Indies in Tests, passing the 411 set by England's Peter May and Colin Cowdrey in 1957 and it soon became the highest for the fourth wicket in all Tests, surpassing Sri Lanka pair Mahela Jayawardene and Thilan Samaraweera's mark of 437 against Pakistan in 2009.
Marsh survived a review for a catch behind but could not go on to 200 as he slog-swept Warrican straight to Bravo at deep mid-wicket. His 266-ball innings featured 15 fours and a six.
The partnership was also the sixth-highest for any wicket in Test cricket, the second-highest for Australia - two runs shy of Donald Bradman and Bill Ponsford's all-time high against England in 1934 - and the highest made on Australian soil.
Marsh's brother Mitchell batted through to lunch with Voges, whose score was the highest at the Bellerive Oval, the fourth highest ever made in a Test against the Windies and the second-highest in Tests this year, behind Ross Taylor's 290 for New Zealand against Australia last month.
Early wickets were not what the West Indies innings required, faced with such an imposing total, but Kraigg Brathwaite made just two before being trapped lbw by Josh Hazlewood.
Rajendra Chandrika and Bravo put on 41 for the second wicket before the former fell to Lyon for 25.
A brilliant return catch, diving to his left, removed Marlon Samuels for nine and later in the same over, he had Jermaine Blackwood caught by short leg by Joe Burns to leave the tourists 78 for four.
That became 89 for five as Denesh Ramdin was bowled by one that kept low from Hazlewood and 116 for six when Holder played around a Siddle delivery and was lbw. Replays showed the ball to be passing over the top of the stumps after hitting the 6ft 7in all-rounder on the knee roll, but he did not review the decision.
Two short rain delays followed, in between which Bravo reached a creditable 107-ball half-century featuring eight fours.
Bravo was six short of a seventh Test century at the close and put on an unbroken partnership of 91 with Roach (31no) but it remains an uphill battle for the tourists.