Messi scored 26 times in El Clasico, the most goals of any player in the history of the fixture.
One Clasico he will remember fondly came on November 29, 2010.
Barcelona welcomed Jose Mourinho’s side to Camp Nou for their La Liga clash.
Barca well and truly blew their fierce rivals away in front of their own fans.
Barcelona dominated the match and ended up crushing Los Blancos 5-0. Messi did not get on the scoresheet but, nevertheless, he put in a strong performance.
Sergio Ramos lost it with Messi in the final moments of the game.
Overcome with frustration, Ramos kicked out at Messi and sent him crashing to the floor.
A brawl broke out and Ramos was shown a red card.
Messi was on the ground for some time but he got to his feet and strolled off the pitch. On his way to the touchline, he walks past eternal rival Cristiano Ronaldo, who stares at him as he walks past.
The camera then pans to Jose Mourinho, who looks glum, before the scoreboard is shown.
A clip of the moment, posted by Twitter user @FutbolLM7, described Messi’s walk as ‘one of the coldest moments in football history’. The video went viral and you can view it below…
When this horrifying Ramos tackle led to one of the coldest moments in football history by Lionel Messi. pic.twitter.com/VBYEdYL4Di— LMθ7 (@FutbolLM7) June 17, 2021
What an iconic moment. That really was El Clasico at its peak. There was drama aplenty during each and every encounter.
View some reaction to the moment below…
Messi and Ramos did not get on very well at all on the pitch during their Barcelona and Real Madrid days.
But they are now teammates at Paris Saint-Germain and appear to have put their differences behind them.
Ramos will be glad he doesn’t have to play against Messi these days. Messi will also be glad he doesn’t have to feel the full force of one of Ramos’ tackles again.
Lionel Messi quiz: How well do you remember his Barcelona career?