Chelsea will take on Tottenham for the first time this season when the two sides meet in the Premier League on Sunday afternoon.

One of the most fierce rivalries in the English top-flight, passions are always high whenever the Blues take on Spurs - and we've seen plenty of flashpoints over the years.

Indeed, 'The Battle of the Bridge' in 2016 - where a staggering 13 yellow cards were handed out - might be the most controversial game in Premier League history.

However, no matter how intense the action is this weekend, something pretty remarkable will have to go down to beat the sheer randomness of Jose Mourinho's interaction with Eric Dier during a League Cup tie between the two sides in 2020.

Entering the final 15 minutes of the round of 16 clash, Mourinho's Tottenham side were trailing by a goal when defender Eric Dier suddenly sprinted off the pitch and down the tunnel.

Nobody knew what to make of the England international's sudden departure - least of all his manager - but the controversial Portuguese coach wasted no time in going to investigate.

Jose Mourinho and Eric Dier at Spurs

LONDON, ENGLAND - DECEMBER 26: Tottenham Hotspur Manager Jose Mourinho talks with Eric Dier during the Premier League match between Tottenham Hotspur and Brighton & Hove Albion at Tottenham Hotspur Stadium on December 26, 2019 in London, United Kingdom. (Photo by Catherine Ivill/Getty Images)

Abandoning his technical area while hollering "Eric", Mourinho chased Dier into the dressing rooms, eager to discover why his man had abandoned his post without notice.

It made for a truly bizarre scene and you can check it out for yourself below.

Watch: Jose Mourinho chases Eric Dier after Spurs defender sprints off the pitch v Chelsea

Although Chelsea's Callum Hudson-Odoi squandered a chance to double his side's lead during Dier's absence, no damage was done by the time he returned to the pitch around a minute after departing - closely followed by Mourinho.

As it turned out, Dier had simply needed a toilet break. Mourinho, though, still looked fuming when he made his way back into the stadium.

That Dier played a role in Erik Lamela’s equaliser for Spurs shortly afterwards probably put Jose in a slightly better mood. The north Londoners ultimately won the tie 5-4 on penalties.

The Ultimate Jose Mourinho 'Did he say it?' Quiz

After helping his side advance in the competition, Dier was named Man of the Match for his efforts on the night.

Eric Dier Instagram post

The Spurs man later poked fun at his brief vanishing act on Instagram, uploading a photo of his award on top of the toilet he had used during the match, captioned: "The real M.O.M".

Spurs eventually made it all the way to the League Cup final - where they lost 1-0 to Manchester City. Mourinho wasn't in charge, though, having been given the boot by Tottenham less than a week before the final.

Chelsea v Tottenham preview | Via The Football Terrace