The reigning UFC welterweight champion will defend his 175lb belt against Edwards in the main event of UFC 278 at the Vivint Arena in Salt Lake City in the early hours of Sunday morning.
The pair’s second meeting will be a rematch of their unforgettable bout in December 2015, which ended in a boring points win for Usman.
Unsurprisingly Edwards is a huge underdog given the dominant nature of their first fight.
But this time, Bisping thinks it will be a different result, although he admitted there may be an element of bias.
Bisping told his YouTube channel: “It’s a tough fight for both men and I truly am torn.
“I’m friends with Kamaru Usman, I respect his body of work greatly, but if you think I’m gonna sit here on my YouTube channel, being a proud Brit, and pick against Leon Edwards, you’re out of your god damn mind. I gotta do it. I gotta go with team U.K. just to send that positivity into the atmosphere.
“I’ve got Leon Edwards winning via decision. So, there you go. If Leon wins, it’s because he’s going to outpoint him for five rounds.
“If Kamaru wins, it’s probably because he’s gonna rock him with a right hand, take him down and try and ragdoll him on the floor.”
And after watching Usman show some weaknesses in the stand-up against Colby Covington, he is fully expecting Edwards to find opportunities to exploit.
Bisping added: “I think this is a tough fight for both men.
“I don’t think this is gonna be easy. We saw Colby Covington have success with the hands against Kamaru. If Colby has success with his hands against Kamaru then you can bet your bottom dollar that Leon Edwards will have success with his hands or striking against Kamaru.
“He’s gonna have to watch the wrestling. It’s gonna be a dog fight and at some point, as it starts getting later in the rounds, people start to get a little more fatigued, they start making mistakes, people start getting desperate, things start going wrong.”