Jurgen Klopp is preparing his Liverpool side for Monday's big clash with local rivals Manchester United at Anfield, for just the second time in the league since his arrival on Merseyside a year ago.
Although the German enjoyed a 2-0 home win over the Red Devils in the Europa League last campaign, the result in the league was one to forget for the Reds faithful.
Wayne Rooney netted the only goal of the game at the beginning of the year to take all three points from Liverpool on their home turf, and Klopp will be hoping to make amends for that loss by continuing their fine early season form.
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However, if Klopp is to guide the Reds to victory, with the outside possibility that Liverpool could go top if other results go their way, the former Borussia Dortmund boss is going to have to do it without one of his summer signings.
Holland hosted Euro 2016 finalists France on Monday night, but they were unable to recover from going a goal down, following a Paul Pogba strike, with Liverpool midfielder Georgino Wijnaldum forced off after 61 minutes.
The 25-year-old, who joined Liverpool from Championship outfit Newcastle this summer, left the pitch with a limp, after going down with what appeared to be a hamstring injury.
Bas Dost came on as the Liverpool man's replacement, following a brief assessment from the Holland physio, and doubts now remain as to whether the midfielder will be available for Monday night's big showdown with United.
Wijnaldum has been ever-present in the league for Liverpool, so far this campaign, but Klopp may have to make alternative arrangements in what has been an unfortunate timing of injury - much to the inconvenience of Klopp, who would have been eager to have all his regular first team players available.
But while Klopp will be without Wijnaldum, England midfielder Jordan Henderson put in a solid performance in the Three Lions' dominant 2-0 win over Malta, at Wembley on Saturday evening.
How big a loss could Georgino Wijnaldum's absence prove to be for Liverpool? Give your opinion in the comment box below.
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