Jose Mourinho has named a surprisingly strong starting XI to face Manchester City in the EFL Cup on Wednesday night.
Paul Pogba, Zlatan Ibrahimovic and Marcus Rashford have all been picked to start and the Manchester United manager has signalled his intentions to use the derby to improve morale after Sunday's 4-0 defeat to Chelsea.
In comparison, Pep Guardiola has decided to rest some of his big stars despite being on a run of four games without a win.
Nevertheless, the biggest talking point regarding the teamsheets is actually about one man who will definitely not take part.
Henrikh Mkhitaryan hasn't played for the Red Devils since the last meeting between the two Manchester sides in September but was expected to make his comeback at some point tonight.
The Armenian was even with the rest of the team when they met up at the Lowry Hotel earlier in the day but he has still been left out of the final 18-man squad.
It comes on the same day rumours about a possible January exit - just a few months after moving to the club - were circulating and Mkhitaryan's absence tonight is likely to only fuel the speculation further over the next few days.
The former Borussia Dortmund ace has struggled for fitness over the last couple of months but now he is available to play and still isn't getting picked, many of his current club's supporters are increasingly concerned about his future.
There's no doubt about it, another loss for Mourinho and co. tonight and United fans will be even more desperate to see Mkhitaryan feature at the weekend.